You know, Typhoid Mary will be the first (and probably last) character that will benefit from the Netflix shows hating the comics, because her comic look is awful so the show just portraying her as Alice Eve in a dress is preferable to the terrible comic design. Also, kudos to them for not ruining a good villain by putting them in IF. Mary wouldn't fit in the DD show anyway, so she's the kind of d-list villain that is perfect for IF (isn't very interesting, is fairly obscure, and is pretty useless to the other shows anyway).
Since the Netflix shows have already ruined the Hand with IF Season 1 and the Defenders, and the Netflix shows have made Steel Serpent into a drug instead of the name being for IF's main arch enemy, they have no actual villains left for Iron Fist. Hopefully the show won't have a season 3, but if Netflix refuses to cancel it hopefully they'll stick with choosing worthless villains for the worthless show, and not waste anyone that might actually work in one of their better shows like Daredevil or Luke Cage.