My preferred interpretation (which I know contradicts aspects of the franchise) has been that the Queen was basically an avatar for the Collective and as such, 'killing' her on one ship was no big deal because she could just be recreated on another.
What I don't really understand is why, when she's attempting to be seductive, she doesn't choose a form that the individuals she's attempting to seduce might find more attractive...unless she knows things about Janeway and Seven that we don't.
...well, in Seven's case, we have subsequent revelations in
Picard, so I guess the Queen did know things that we didn't...