Why was House upset at Cuddy's news?
I'd say a combo of him not being asked to try and father her child and not being asked to be a reference. Can't say I blame Cuddy for the latter.

Excellent episode, titillation aside (which was great -BTW

It was fun seeing House and Wilson back in regular form.

Awesome.
I love 13.

I still kind of like Argyle Sock PI guy. I think his series will be interesting if/when he gets it.
POTW was an intersting story and her and 13 had some good, touching, and warm scenes together. (Again, titillation aside.)
I'm still "hoping" for a turn-around on 13's Hutchingtons diagnosis. Either a (completely fictional) cure, discovery that her tests have been false positives or House discovering she has some other condition that caused false positives.
I did note that when House cut the onion that HIS eyes didn't tear up.

