[Update: We’ve now learned from trusted sources four more actresses who are testing for the role of Domino in Deadpool 2, in addition to the six we reported previously: Mackenzie Davis (Halt and Catch Fire), Ruby Rose (Orange Is the New Black), Eve Hewson (The Knick), and Kelly Rohrbach (Baywatch). Our original story follows below.]
While the sequel doesn’t yet have a firm release date, development is moving right along on Deadpool 2, and director Tim Miller and the film’s producers are now looking towards casting a key female role. Sources close to the production exclusively tell Collider that testing has begun for the character of Domino, and the actresses under consideration include Lizzy Caplan (Masters of Sex), Mary Elizabeth Winstead (10 Cloverfield Lane), Sienna Miller (American Sniper), Sofia Boutella (Star Trek Beyond), Stephanie Sigman (Spectre), and Sylvia Hoeks (Overspel). There could be other actresses included in the mix, but sources tell us that at least these six performers have tested or are going to test for the role.
http://collider.com/deadpool-2-domino-casting/